Rabbit Anti- Adiponectin Receptor 2
脂联素受体2抗体/ Anti- Adiponectin Receptor 2
Adipo R2; Progestin and adipoQ receptor family member II; Adipor2; PAQR2; ADR2_HUMAN.
0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide；Reconstitute with 0.1ml sterile distilled water.
免 疫 原：
KLH conjugated synthetic peptide derived from human Adiponectin receptor 2 (315-340aa)
Human, Mouse, Rat, Dog, Pig
Lyophilized or Liquid
分 子 量：
Predicted molecular weight 44kDa
affinity purified by Protein A
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Use a manual defrost freezer and avoid repeated freezethaw cycles.
1 month from date of receipt, 2 to 8℃, reconstituted.
6 months from date of receipt, -20 to -70℃, reconstituted.
12 months from date of receipt, -20 to -70℃as supplied.
When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM, Mar 2008]
Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.
May form homo and heteromultimers.
Membrane; Multi-pass membrane protein. Note=Localized to the cell membrane and intracellular organelles.
Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
Belongs to the ADIPOR family.
Tissue/cell: rat pancreas tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Tissue/cell: human rectal tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;