Rabbit Anti- ADRA2
ADRA2肾上腺素能受体2抗体/ Anti- ADRA2
alpha-2A adrenergic receptor; alpha 2a Adrenergic Receptor; ADRA2A; ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32; RATRG20; RG20; Adrenergic alpha 2A receptor; Alpha 2AAR subtype C10; OTTHUMP00000058849; ADA2A_HUMAN; Alpha-2A adrenergic receptor; Alpha-2 adrenergic receptor subtype C10; Alpha-2A adrenoreceptor; Alpha-2A adrenoceptor; Alpha-2AAR.
0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide；Reconstitute with 0.1ml sterile distilled water.
免 疫 原：
KLH conjugated synthetic peptide derived from human ADRA2
Human, Mouse, Rat, Pig, Cow, Rabbit
Lyophilized or Liquid
分 子 量：
Predicted molecular weight 50kDa
affinity purified by Protein A
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Use a manual defrost freezer and avoid repeated freezethaw cycles.
1 month from date of receipt, 2 to 8℃, reconstituted.
6 months from date of receipt, -20 to -70℃, reconstituted.
12 months from date of receipt, -20 to -70℃as supplied.
When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha 2A, alpha 2B, and alpha 2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha 2A and alpha 2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha 2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha 2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha 2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq].
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily.
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Protein: line1, rat kidney lysates, 30ug; line2, rat brain lysates, 30ug;